The CBV response begins by the first image after stimulus onset, and has significantly narrower dispersion and shorter TTP than the BOLD curve. Longer delays were measured in large pial veins in the BOLD maps.(c) Across-subject (n=5) averaged BOLD (black) and CBV (gray) fMRI IRs. (b) Corresponding TTP maps for BOLD (left) and CBV (right). The CBV FWHM map is much more homogeneous. There is significant heterogeneity in the BOLD FWHM, with the middle layers of the cortex showing the shortest widths and the peripheral regions showing extended spread. (Above) Measurement of the fMRI Impulse Response in a Rat Model of Somatosensory Stimulation:Ī) Typical FWHM maps for BOLD (left) and CBV (right). Investigation of the Spatial and Temporal Specificity of Functional Hemodynamic Signals:
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